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Pesticides ‘linked to Parkinson’s’

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Pesticides ‘linked to Parkinson’s’

A pesticide is a substance or mixture of substances used to kill a pest.[1] A pesticide is any substance or mixture of substance intended for: – preventing, destroying, repelling or mitigating any pest.[2] A pesticide may be a chemical substance, biological agent (such as a virus or bacteria), antimicrobial, disinfectant or device used against any pest. Pests include insects, plant pathogens, weeds, molluscs, birds, mammals, fish, nematodes (roundworms), microbes and people that destroy property, spread or are a vector for disease or cause a nuisance. Although there are benefits to the use of pesticides, there are also drawbacks, such as potential toxicity to humans and other animals.

2,4-Dichlorophenoxyacetic acid – known as 2,4-D – used to kill a range of weeds

Permethrin – used in pest control, including ant powder and flea killer. Sprayed on tents and nets to repel mosquitoes

Paraquat – weedkiller used on a range of crops including potatoes. Banned for use in Europe since 2007

Dieldrin – pesticide, banned for use in Europe

Diquat – general weedkiller

Maneb – kills fungus, used to protect potatoes, tomatoes and other crops

Mancozeb – also kills fungus, used to protect potatoes among other crops

Rotenone – used to eradicate unwanted fish species as well as other pests

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Doubts on suicide-anti-smoking drug Chantix link

in.reuters.com

Doubts on suicide-anti-smoking drug Chantix link

Despite earlier health agency warnings, there is no strong evidence that the anti-smoking drug Chantix raises the risk of suicidal thoughts or depression compared to other stop-smoking products, researchers reported Thursday in the British Medical Journal.

Back in July of this year, U.S. health officials ordered strong “black box” warnings be added to Chantix (also called varenicline) as well as anti-smoking drug Zyban, following more than five thousand reports of depression, hostility and other behavioral changes possibly associated with use of these drugs.

“There have been recent concerns that varenicline, a relatively new smoking cessation product, may increase the risk of suicidal behavior and suicide,” study co-author Dr. David Gunnell of the University of Bristol, UK, explained in an email to Reuters Health.

“We found no clear evidence of an increased risk of self-harm or depression associated with varenicline,” he said.

The findings stem from data on more than 80,660 would-be quitters in the UK who used different smoking cessation products between September 2006 and May 2008.

A total of 63,265 of these individuals used nicotine replacement products, 10,973 used Chantix, and 6,422 used Zyban, an antidepressant also called bupropion, which has been found to help smokers quit.

When researchers looked at medical records, they didn’t find any evidence of an increased risk of serious mental health problems (i.e., self-harm, suicidal thoughts or depression) while they were using these products and during the three months after the last prescription was filled.

Gunnell cautioned, however, that based on the size of the study, it’s still possible that Chantix does increase the risk of suicide – or even decrease it.

“Other studies should be undertaken to provide further evidence on this issue,” he concluded.

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Only 10 percent of U.S. adults have low heart risk

in.reuters.com

Only 10 percent of U.S. adults have low heart risk

Ninety percent of American adults have at least one risk factor for heart disease, researchers reported on Monday.

Virtually all Americans either have high blood pressure, high cholesterol, high blood sugar, are overweight, smoke or exercise too little, the team led by the Centers for Disease Control and Prevention reported.

“Unfortunately, the limited strides that were made toward this goal during the 1970s and 1980s were eroded by the increases in excess weight, diabetes and hypertension during more recent decades,” the CDC’s Dr. Earl Ford, who led the study, said in a statement.

Ford’s team looked at four national studies covering tens of thousands of Americans aged 25 to 74.

Only 10 percent had low risk scores in all five categories, they reported in the journal Circulation.

“Until the early 90s, we were moving in a positive direction, but then it took a turn and we’re headed in a negative direction,” said Ford.

“When you look at the individual factors, tobacco use is still headed in the right direction and so are cholesterol levels, although that has leveled off. The problem is that blood pressure, BMI (body mass index, a measure of obesity) and diabetes are all headed in the wrong direction.”

Heart disease is the No. 1 killer in the United States and many other countries.

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