Tag Archives: speed

Pumping Heart

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Pumping Heart

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A pump is a device used to move fluids, such as gases, liquids or slurries. A pump displaces a volume by physical or mechanical action. One common misconception about pumps is the thought that they create pressure. Pumps alone do not create pressure; they only displace fluid, causing a flow. Adding resistance to flow causes pressure. Pumps fall into two major groups: positive displacement pumps and rotodynamic pumps. Their names describe the method for moving a fluid.

A positive displacement pump causes a fluid to move by trapping a fixed amount of it then forcing (displacing) that trapped volume into the discharge pipe. A positive displacement pump can be further classified according to the mechanism used to move the fluid:

Rotary-type, for example, the lobe, external gear, internal gear, screw, shuttle block, flexible vane or sliding vane, helical twisted roots (e.g. the Wendelkolben pump) or liquid ring vacuum pumps.

Positive displacement rotary pumps are pumps that move fluid using the principles of rotation. The vacuum created by the rotation of the pump captures and draws in the liquid. Rotary pumps are very efficient because they naturally remove air from the lines, eliminating the need to bleed the air from the lines manually. Positive displacement rotary pumps also have their weaknesses. Because of the nature of the pump, the clearance between the rotating pump and the outer edge must be very close, requiring that the pumps rotate at a slow, steady speed. If rotary pumps are operated at high speeds, the fluids will cause erosion, much as ocean waves polish stones or erode rock into sand. Rotary pumps that experience such erosion eventually show signs of enlarged clearances, which allow liquid to slip through and detract from the efficiency of the pump. Positive displacement rotary pumps can be grouped into three main types. Gear pumps are the simplest type of rotary pumps, consisting of two gears laid out side-by-side with their teeth enmeshed.

The gears turn away from each other, creating a current that traps fluid between the teeth on the gears and the outer casing, eventually releasing the fluid on the discharge side of the pump as the teeth mesh and go around again. Many small teeth maintain a constant flow of fluid, while fewer, larger teeth create a tendency for the pump to discharge fluids in short, pulsing gushes. Screw pumps are a more complicated type of rotary pumps, featuring two screws with opposing thread —- that is, one screw turns clockwise, and the other counterclockwise. The screws are each mounted on shafts that run parallel to each other; the shafts also have gears on them that mesh with each other in order to turn the shafts together and keep everything in place. The turning of the screws, and consequently the shafts to which they are mounted, draws the fluid through the pump. As with other forms of rotary pumps, the clearance between moving parts and the pump’s casing is minimal. Moving vane pumps are the third type of rotary pumps, consisting of a cylindrical rotor encased in a similarly shaped housing. As the rotor turns, the vanes trap fluid between the rotor and the casing, drawing the fluid through the pump.

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Infections may speed Alzheimer’s memory loss

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Infections may speed Alzheimer’s memory loss

Catching a cold or the flu could speed memory loss in people with Alzheimer’s disease, researchers reported Tuesday.

In a study of patients with mild to severe Alzheimer’s disease, they found that people who suffered acute or chronic infections, or even bumps and bruises from a fall, were much more likely to have high blood levels of a protein involved in inflammation and also experienced faster memory loss than people who did not have infections and who had low levels of this protein.

It’s possible that finding a way to reduce inflammation in the body “could be beneficial for people with Alzheimer’s disease,” study chief Dr. Clive Holmes, from the University of Southampton, UK, said in a prepared statement.

Over about 6 months, Holmes and colleagues measured the cognitive abilities and blood levels the inflammatory protein TNF-alpha of 222 people with Alzheimer’s disease. They also interviewed each subject’s main caregiver several times during the study.

During follow up, roughly half of the study subjects experienced a sudden infection or injury that led to inflammation, and a spike in TNF-alpha levels. These people, the researchers found, experienced memory loss that was at twice the rate of those who did not have infections or injuries.

People who had high levels of TNF-alpha in their blood at the beginning of the study, a sign of chronic, ongoing inflammation, had memory loss at four times the rate of those with low levels of the protein at the start of the study.

By contrast, subjects with low levels of TNF-alpha throughout the study showed no decline in brain function, the report indicates.

“One might guess that people with a more rapid rate of cognitive decline are more susceptible to infections or injury, but we found no evidence to suggest that people with more severe dementia were more likely to have infections or injuries at the beginning of the study,” Holmes noted in a prepared statement.

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