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More kids have autism than thought: U.S. study

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More kids have autism than thought: U.S. study

You may have heard the oft-quoted statistic that autism affects 1 in 150 US children. Turns out it’s more like 1 in 91 — and about 1 in 58 boys, according to new figures released Sunday.

That’s an estimated 673,000 US children — or approximately 1 percent of all U.S. kids, the researchers from the U.S. Centers for Disease Control and Prevention, Atlanta, and Harvard Medical School, Boston report in the journal Pediatrics.

Bob Wright, co-founder of the autism advocacy group Autism Speaks, told Reuters Health he’s not at all surprised by the new figures. “We’ve been screaming about the numbers going up; now there is a relatively complete recognition of it.”

“The statistical aspect of autism is just staggering,” he said, and not enough is being done about it. “If we had 1 in 58 boys getting swine flu, the country would be crazy,” Wright said.

Autism is a brain disorder characterized by problems with social interaction, repetitive behavior and other symptoms. People with a mild version called Asperger’s syndrome usually function relatively well in society, although they have problems relating to others. People with the most extreme symptoms may be unable to speak and may also suffer severe mental illness and retardation.

No one knows what causes autism — it’s generally thought to have genetic and environmental triggers — and there is currently no good treatment.

Autism is “an urgent public health concern,” Dr. Ileana Arias, deputy director of CDC, told reporters on a conference call Friday ahead of public release of the data.

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Australia reports first Tamiflu-resistant H1N1 case

Australia reports first Tamiflu-resistant H1N1 case

The first Australian case of swine flu resistant to Roche Holding AG’s antiviral drug Tamiflu was confirmed by the Western Australia state government on Friday.

“The 38-year-old Perth man, who has a weakened immune system, initially responded to the drug but developed a resistant strain of the virus when his illness relapsed,” the state’s Department of Health said in a statement.

There have been 13 cases of Tamiflu-resistant infections around the world, the statement said.

A Roche executive said on Monday that isolated cases of Tamiflu-resistant H1N1 pandemic flu were to be expected, in line with what has been seen in clinical studies.

“There is no evidence that the virus has spread to other people. None of the patient’s family or hospital staff caring for him have contracted the virus, and he has not been in contact with the wider community,” said the state’s Chief Health Officer Tarun Weeramanthri, adding that the case was a rare and isolated one.

The man remained in a critical condition in intensive care.

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Tamiflu saves lives of severely ill flu patients

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Tamiflu saves lives of severely ill flu patients

Roche AG’s antiviral drug Tamiflu helped prevent deaths from seasonal flu in severely ill patients who had chronic underlying health problems, Chinese researchers said on Sunday.

A study of 760 older, severely ill patients in Hong Kong found that Roche and Gilead Sciences Inc’s drug Tamiflu cut the rate of death by 37 percent.

More than 60 percent of patients in the study had underlying chronic illnesses, and 78 percent had been hospitalized with complications from seasonal flu.

The study, done by researchers at the Chinese University of Hong Kong and presented at the Interscience Conference on Antimicrobial Agents and Chemotherapy in San Francisco, suggests the drug can help save the lives of seriously ill flu patients, Dr David Reddy, who leads Roche’s pandemic flu task force, said in a telephone briefing.

Known generically as oseltamivir, Tamiflu is one of two antiviral drugs that work well against H1N1 swine flu.

The study took place in two hospitals in Hong Kong between 2007 and 2008. About half the patients in the study got Tamiflu and half got no treatment. Death rates were about the same at both hospitals.

“In this study, Tamiflu improved the survival rate by reducing the rate of death by 37 percent in this high-risk group of patients with severe seasonal flu compared to no treatment,” Reddy said.

The U.S. Centers for Disease Control and Prevention is recommending that the very old and people with chronic medical conditions should be treated with antiviral drugs — either Tamiflu or GlaxoSmithKline and Biota’s Relenza — when they have flu-like symptoms.

Health officials caution against using either drug in otherwise healthy people who have moderate or mild flu symptoms, however, because of the fear of resistance. Influenza viruses very quickly change to put up a strong defense against antiviral drugs. Last year the seasonal H1N1 virus developed strong resistance to Tamiflu. Two older flu drugs, amantadine and rimantadine, now have very little effect against influenza viruses.

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