Tag Archives: flu drugs

Tamiflu saves lives of severely ill flu patients

October 25, 2013Fluand, antimicrobial agents and chemotherapy, antiviral drugs, beating, bf1, blister, calories, Cancer, centers for disease control and prevention, chinese researchers, chinese university of hong kong, chronic illnesses, chronic medical conditions, david reddy, diet, Drug, drugs, eating, Exercise, Exercising for Weight Gallery, Exercising for Weight Health Story, Exercising for Weight Health Photo, Exercising Weight, Flu, flu drugs, flu like symptoms, flu patients, flu symptoms, for, gallery, gilead sciences, gilead sciences inc, Gym, Health Health, health video, Healthy Minnesota, Healthy Minnesota Asia, Healthy Minnesota Health Story, Healthy Minnesota Photo Gallery, high risk group, history, hospitals in hong kong, ill, in, interscience conference on antimicrobial agents and chemotherapy, laparoscopy, lives, Malaysia Health, medical, mild flu, Nutrition, of, operation, organic, Pandemic Flu, patients, photo, physical, saves, severely, skin, spiritual, study, Surgery, swine flu, symptoms, tamiflu, Tamiflu saves, Tamiflu saves Asia, Tamiflu saves Gallery, Tamiflu saves Health, Tamiflu saves Health History, Tamiflu saves Health Information, Tamiflu saves Health Latest, Tamiflu saves Photo Gallery, Tamiflu saves Picture, Tamiflu saves Video, Tamiflu saves Web, Tamiflu savesHealth latest, Tamiflu savesHealth Photo, Tamiflu savesover Picture, tips, training, video, video photo, video surgery, virus, web Health, web Health picture, weightlossazuan

Tamiflu saves lives of severely ill flu patients

Roche AG’s antiviral drug Tamiflu helped prevent deaths from seasonal flu in severely ill patients who had chronic underlying health problems, Chinese researchers said on Sunday.

A study of 760 older, severely ill patients in Hong Kong found that Roche and Gilead Sciences Inc’s drug Tamiflu cut the rate of death by 37 percent.

More than 60 percent of patients in the study had underlying chronic illnesses, and 78 percent had been hospitalized with complications from seasonal flu.

The study, done by researchers at the Chinese University of Hong Kong and presented at the Interscience Conference on Antimicrobial Agents and Chemotherapy in San Francisco, suggests the drug can help save the lives of seriously ill flu patients, Dr David Reddy, who leads Roche’s pandemic flu task force, said in a telephone briefing.

Known generically as oseltamivir, Tamiflu is one of two antiviral drugs that work well against H1N1 swine flu.

The study took place in two hospitals in Hong Kong between 2007 and 2008. About half the patients in the study got Tamiflu and half got no treatment. Death rates were about the same at both hospitals.

“In this study, Tamiflu improved the survival rate by reducing the rate of death by 37 percent in this high-risk group of patients with severe seasonal flu compared to no treatment,” Reddy said.

The U.S. Centers for Disease Control and Prevention is recommending that the very old and people with chronic medical conditions should be treated with antiviral drugs — either Tamiflu or GlaxoSmithKline and Biota’s Relenza — when they have flu-like symptoms.

Health officials caution against using either drug in otherwise healthy people who have moderate or mild flu symptoms, however, because of the fear of resistance. Influenza viruses very quickly change to put up a strong defense against antiviral drugs. Last year the seasonal H1N1 virus developed strong resistance to Tamiflu. Two older flu drugs, amantadine and rimantadine, now have very little effect against influenza viruses.

Tamiflu saves, Tamiflu saves Health, Tamiflu saves Health Latest, Tamiflu saves Health Information, Tamiflu saves Health information, Tamiflu savesHealth Photo,Exercising for Weight Health photo, Tamiflu saves Health Latest, Tamiflu savesHealth latest, Exercising for Weight Health Story, Healthy Minnesota Health story, Tamiflu saves Video, Tamiflu saves video, Tamiflu saves Health History, Tamiflu saves Health history, Tamiflu savesover Picture, history, Tamiflu saves Asia, Healthy Minnesota asia, Tamiflu saves Gallery, Exercising for Weight gallery, Tamiflu saves Photo Gallery, Healthy Minnesota photo gallery, Tamiflu saves Picture, Tamiflu saves picture, Tamiflu saves Web, Malaysia Health, web Health, web Health picture, video photo, video surgery, gallery, laparoscopy, virus, flu, drug, video, Health Health, calories, photo, nutrition, health video, symptoms, cancer, medical, beating, diet, physical, Training, organic, gym, blister, exercise, weightloss, surgery, spiritual, eating, tips, skin, operation, bf1, Tamiflu, saves, lives, of, severely, ill, flu, patients

stress quick treatment for H1N1

stress quick treatment for H1N1

Patients who have flu-like symptoms and are having trouble breathing should get quick treatment with the antiviral drugs Tamiflu or Relenza, even before getting a flu test, U.S. officials said on Tuesday.

And doctors should consider setting up a system so that patients most likely to become severely ill from H1N1 swine flu have a prescription on hand so they can just call up to get the go-ahead to take the drugs if they develop symptoms, the U.S. Centers for Disease Control and Prevention said.

“Treatment should not wait for laboratory confirmation of influenza because laboratory testing can delay treatment and because a negative rapid test for influenza does not rule out influenza,” the CDC says in updated guidelines, available here

“The very young and very old, people with chronic medical conditions and pregnant women in general ought to be treated with antivirals when they have an influenza-like illness,” the CDC’s Dr. Anne Schuchat told reporters.

But most people will not need any treatment at all for H1N1 because most of those infected so far have recovered on their own. “They can be cared for with mom’s chicken soup at home, lots of fluids and rest,” Schuchat said.

The latest guidance suggests officials are keen to make sure people who need it get very quick treatment, while making sure people who do not need the drugs do not abuse them.

Both GlaxoSmithKline’s Relenza and Roche AG’s Tamiflu can help save the lives of patients severely ill with any influenza, if given within a day or so of symptoms starting. They can also ease the misery of milder cases and even prevent flu if people take it just after exposure.

But supplies are not infinite and health officials worry that the more people take them, the quicker the virus will evolve resistance, rendering them useless. Two older flu drugs, amantadine and rimantadine, are already useless against seasonal flu.

The CDC is clear that some people should take the drugs prophylactically — to prevent infection. That includes some healthcare workers and people with high-risk conditions such as asthma who know they were in close contact with an infected person.

But the new guidance adds an option to watch and see if the person gets a fever. “Instead of the preventive use of antivirals, clinicians may consider watchful waiting,” Schuchat said.

A vaccine against H1N1 swine flu is being tested but will not be available until mid-October. The CDC recommends that about 160 million people line up for the first doses starting then.

“Virtually all the influenza circulating now in the United States is the 2009 H1N1 strain,” Schuchat said. It has not mutated and the vaccine is still a good match, she said.

She said only a handful of cases of resistance to Tamiflu, known generically as oseltamivir, have been reported.

In the United States, 24 elementary, middle or high schools closed because of H1N1 outbreaks last week, letting 25,000 students out of class. The CDC advises against closing schools unless so many students or staff become ill that the school is overwhelmed.

stress quick treatment , stress quick treatment Health, stress quick treatment Health Latest, stress quick treatment Health Information, stress quick treatment Health information, stress quick treatment Health Photo,Exercising for Weight Health photo, stress quick treatment Health Latest, stress quick treatment Health latest, Exercising for Weight Health Story, Healthy Minnesota Health story, stress quick treatment Video, stress quick treatment video, stress quick treatment Health History, stress quick treatment Health history, stress quick treatment over Picture, history, stress quick treatment Asia, Healthy Minnesota asia, stress quick treatment Gallery, Exercising for Weight gallery, stress quick treatment Photo Gallery, Healthy Minnesota photo gallery, stress quick treatment Picture, stress quick treatment picture, stress quick treatment Web, Malaysia Health, web Health, web Health picture, video photo, video surgery, gallery, laparoscopy, virus, flu, drug, video, Health Health, calories, photo, nutrition, health video, symptoms, cancer, medical, beating, diet, physical, Training, organic, gym, blister, exercise, weightloss, surgery, spiritual, eating, tips, skin, operation, bf1, stress, quick, treatment, for, H1N1

New flu drug may resist mutations: researchers

October 10, 2013Fluamantadine and rimantadine, and, antimicrobial agents and chemotherapy, antiviral drugs, beating, bf1, blister, calories, Cancer, centers for disease control and prevention, company spokesman, diet, Drug, drugs, eating, Exercise, Exercising for Weight Gallery, Exercising for Weight Health Story, Exercising for Weight Health Photo, Exercising Weight, Flu, flu drug, flu drugs, flu virus, fludase, for, gallery, Gym, H1N1, Health Health, Health Latest, health video, Healthy Minnesota, Healthy Minnesota Asia, Healthy Minnesota Health Story, Healthy Minnesota Photo Gallery, history, human cells, in, influenza drug, influenza virus, interscience conference on antimicrobial agents and chemotherapy, lab dishes, laparoscopy, Malaysia Health, may, medical, molecular doorway, mutations, New flu, New flu drug, New flu drug Asia, New flu drug Gallery, New flu drug Health, New flu drug Health History, New flu drug Health Information, New flu drug Health Latest, New flu drug Photo Gallery, New flu drug Picture, New flu drug Video, New flu drug Web, New flu drug Health Photo, New flu drug over Picture, nexbio inc, Nutrition, of, on, operation, organic, photo, physical, relenza, researchers, resist, rimantadine, saint louis university, skin, spiritual, Surgery, swine flu, symptoms, tips, to, training, video, video photo, video surgery, virus, web Health, web Health picture, weightlossazuan

New flu drug may resist mutations: researchers

A new type of experimental flu drug that stops the virus from infecting cells appears to stop it from mutating into drug-resistant forms, researchers reported on Sunday.

Tests in mice and in lab dishes show that NexBio Inc.’s drug Fludase can stop the seasonal influenza virus from infecting cells and can fight strains of virus that have evolved resistance to Tamiflu, Roche AG’s popular influenza drug, the company said.

“Extensive, prolonged nonclinical influenza studies have not shown the development of any meaningful resistance,” the company said in a statement released at the Interscience Conference on Antimicrobial Agents and Chemotherapy in San Francisco.

Privately held NexBio Inc. said tests showed that Fludase, also known as DAS181, worked against the new H1N1 swine flu virus too.

Influenza viruses very quickly change to put up a strong defense against antiviral drugs. Last year the seasonal H1N1 virus developed strong resistance to Tamiflu. Two older flu drugs, amantadine and rimantadine, now have very little effect against influenza viruses.

Tamiflu and a similar drug, GlaxoSmithKline’s Relenza, affect a compound in the flu virus called neuraminadase — which gives flu viruses like H1N1 the “N” in their names.

Fludase affects the human cells that influenza infects, not the virus itself and that should make it less likely to cause the virus to develop resistance, company spokesman Dr. David Wurtman said.

It affects the sialic acid receptor — the molecular doorway that flu viruses use to attach to cells, he said.

“It makes it impossible to spread, so it can’t infect neighboring cells,” Wurtman said in a telephone interview.

Teams at the U.S. Centers for Disease Control and Prevention, University of Hong Kong and Saint Louis University in Missouri ran the experiments, the company said.

“Based on these encouraging data, we are moving forward with our ongoing clinical development of DAS181, and we will continue to work closely with FDA (the U.S. Food and Drug Administration), CDC and NIH (the National Institutes of Health) on this clinical program during the current pandemic,” Dr. Ronald Moss of NexBio, who presented the study, said in a statement.

Health experts predict that new drugs to fight flu will soon be needed, as the virus is mutation prone. Many are in development — furthest along is BioCryst’s peramivir, which would be made and sold in partnership with Japan’s Shionogi.

New flu drug , New flu drug Health, New flu drug Health Latest, New flu drug Health Information, New flu drug Health information, New flu drug Health Photo,Exercising for Weight Health photo, New flu drug Health Latest, New flu drug Health latest, Exercising for Weight Health Story, Healthy Minnesota Health story, New flu drug Video, New flu drug video, New flu drug Health History, New flu drug Health history, New flu drug over Picture, history, New flu drug Asia, Healthy Minnesota asia, New flu drug Gallery, Exercising for Weight gallery, New flu drug Photo Gallery, Healthy Minnesota photo gallery, New flu drug Picture, New flu drug picture, New flu drug Web, Malaysia Health, web Health, web Health picture, video photo, video surgery, gallery, laparoscopy, virus, flu, drug, video, Health Health, calories, photo, nutrition, health video, symptoms, cancer, medical, beating, diet, physical, Training, organic, gym, blister, exercise, weightloss, surgery, spiritual, eating, tips, skin, operation, bf1, New flu, drug, may, resist, mutations, researchers