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No treatment ‘not an option’ for ailing mum

October 10, 2013Careailing, an, and, beating, bf1, blister, bronchial tube, calories, Cancer, cancer diagnosis, chemotherapy, co ordinator, diet, district health board, Drug, eating, elder daughter, Exercise, Exercising for Weight Gallery, Exercising for Weight Health Story, Exercising for Weight Health Photo, Exercising Weight, Flu, for, free options, gallery, girls, Gym, Health Health, health video, Healthy Minnesota, Healthy Minnesota Asia, Healthy Minnesota Health Story, Healthy Minnesota Photo Gallery, heart, heart beat, heart block, history, hospice care, hospice team, in, is, jazmin, laparoscopy, lung cancer, Malaysia Health, medical, Mrs Stanton, mum, No, No treatment, No treatment Asia, No treatment Gallery, No treatment Health, No treatment Health History, No treatment Health Information, No treatment Health Latest, No treatment Photo Gallery, No treatment Picture, No treatment Video, No treatment Web, No treatmentHealth latest, No treatmentHealth Photo, No treatmentover Picture, non residents, non small cell carcinoma, not, Nutrition, of, operation, option' for, organic, palmerston north, photo, physical, radiation treatment, roller coaster ride, skin, small cell carcinoma, spiritual, Surgery, symptoms, tips, to, training, treatment, trial, video, video photo, video surgery, virus, web Health, web Health picture, weightloss, whakapapa, x raysazuan

No treatment ‘not an option’ for ailing mum

Palmerston North’s Tarsh Stanton has run out of free options in her fight against cancer, and is looking for help to get to Melbourne to take part in a potentially lifesaving trial.

Within a year she has gone from being an active mother of two girls to what she describes as a steroid-puffed “blowfish”.

She’s in hospice care but determined to overcome stage four relapsed lung cancer that has spread to other organs.

She’s still working full time as ACC and non-residents co-ordinator at the MidCentral District Health Board, but chemotherapy and radiation treatment have failed to deliver on the 15 to 20 per cent chance of beating the cancer.

Only ever having had a few social puffs on cigarettes years ago, she said her cancer diagnosis came as a shock after what was either a lucky or unlucky cold.

She came home from a school camp at Whakapapa with her daughter Jazmin with an illness that became worse and made breathing difficult. Elder daughter Chelsea took her to the doctor, and the roller-coaster ride began.

Her heart beat was way too slow, and she was transferred to Wellington. She had a heart block that had to be corrected with a pacemaker last September.

X-rays showed shadows that were diagnosed as lung cancer adenosquamous non-small cell carcinoma. She was 36.

She’s had chemotherapy and radiation treatment, which has shrunk the cancer, but not stopped its spread to her other lung and bronchial tube, liver and stomach lining.

Reluctantly agreeing to be referred to the hospice team to fast track the process when she needs help with symptoms, such as the pain caused by the fluid building up between her ribs and lungs, she’s not ready to give up.

“The hospice is where you go to die, and I’m not going there,” she said.

“I’m quite relaxed. It’s not denial. I know what I’ve got, and I’m fully informed.

“I don’t like it much, but I can’t change it, and there’s no point in being sad and unfocused.”

Supported by a group of well-wishers led by her cousin Kelly Retter, Mrs Stanton has researched her options all of which cost money.

“No treatment is not an option.”

Her best hope in New Zealand is the unsubsidised drug Tarceva, which works like a sort of cling wrap encasing and constricting cancer cells, and offers a 40 per cent hope for patients who respond well. It costs about $28,000 a year.

But even more attractive is a phase II clinical trial at the Peter MacCullum Cancer Centre in Melbourne that combines Tarceva with a new biological ingredient that doesn’t even have a name yet.

Although participation is covered by drug company Roche, Mrs Stanton faces travel and accommodation costs for herself and a caregiver to travel to Melbourne for 25 appointments over two years.

Moving to Australia, where Tarceva is subsidised, is not an option.

“I’m a Kiwi. I live here, I work here, and I want to keep working. Time is precious, that’s one of the things this teaches you.

“If you only have so long to live, why would you want to spend it in Australia?”

At the moment Mrs Stanton is back in chemotherapy at Palmerston North Hospital because her cancer is too advanced to do nothing.

But once she gets the all-clear for the trial, she has to be chemo-free for a month before starting.

It’s a balancing act, as she has to be sick enough to qualify, yet well enough to tolerate the travel and treatment.

She’s hoping for Christmas in Palmerston North with husband Darren, and the girls, now aged 13 and 17, but if the trial schedule demands she be in Melbourne, she will be.

It’s a course she’s setting out on full of optimism.

“Eighty-six is my goal. It’s just a good number for sitting back in your rocking chair, drinking vodka.”

Her fundraising team is organising an October concert and a November auction to help pay for the $60,000 travel and expenses bills she’s likely to face.

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How broccoli can protect your arteries

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How broccoli can protect your arteries

It’s long been thought that broccoli is good for your heart, and now British scientists think they know why.

Researchers at Imperial College London have found evidence a chemical in broccoli and other green leafy vegetables could boost a natural defense mechanism that protects arteries from the clogging that can cause heart attacks.

In a study funded by the British Heart Foundation charity and conducted on mice, the researchers found that sulforaphane — a compound occurring naturally in broccoli and other brassicas — could “switch on” a protective protein which is inactive in parts of the arteries vulnerable to clogging.

“We know that vegetables are clearly good for you, but surprisingly the molecular mechanisms of why they are good for you have remained unknown for many years,” said Paul Evans of the National Heart and Lung Institute at Imperial College.

“This study provides a possible explanation for how green vegetable consumption can promote a healthy heart.”

Scientists already know that arteries don’t clog up in a uniform way, but that there are bends and branches of blood vessels — where blood flow is disrupted or slower — which are much more prone to the build-up of fatty plaques that cause heart disease.

Evans said his research found that in the more vulnerable areas, a normally protective protein known as Nrf2 is inactive.

“What our study showed was that sulforaphane can protect those regions by switching on the Nrf2,” he said.

The research, reported in the journal Arteriosclerosis Thrombosis and Vascular Biology, was conducted using purified sulforaphane, not broccoli. Researchers said the next step was to test the effect of the chemical as it is found in vegetables.

We now need to go and test this with broccoli smoothies, as it were, and compare that with the effect of purified sulforaphane,” Evans said, adding that if the vegetable form proved less effective, there could be an argument for taking sulforaphane in pill form.

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Thin thighs – maybe not your heart’s desire

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Thin thighs – maybe not your heart’s desire

People who have agonized over their fat thighs might be able to relax a bit — Danish doctors said on Thursday they found patients with the thinnest thighs died sooner than the more endowed.

Obesity, age, smoking and other factors did not reduce the effect, the researchers reported in the British Medical Journal.

“Our results suggest that there might be an increased risk of premature death related to thigh size,” Berit Heitmann of Copenhagen University Hospital and Peder Frederiksen of Glostrup University Hospital wrote.

The explanation may lie in many different studies that suggest where you gain your weight is a strong factor in how it affects health. People with lots of abdominal fat — wrapped in and around the internal organs — appear to be at higher risk of heart disease, diabetes, and other ills.

So-called pear-shaped people may have lower risks, even if they have more body fat overall.

Heitmann and Frederiksen studied 1,436 men and 1,380 women taking part in a larger medical research study who were examined in 1987 and 1988, then watched them for more than 12 years.

Men and women whose thighs were less than 24 inches in circumference were more likely to die during those 12 years, they found.

Those with the thinnest thighs — less than 18 inches — were more than twice likely to have died within 12 years, they reported in the study, published here

Dozens of studies have shown waist size can also be a good predictor of heart disease and death.

Women with a waist circumference of greater than 35 inches and men whose waists are more than 40 inches have a much higher risk of heart disease, diabetes and early death than people with smaller waists — regardless of how much body fat they have overall.

This is again linked to abdominal fat. Fat laid down under the skin, as when it is found on the legs, may be healthier for the body, although the mechanism is unclear.

The Danish team said they hoped thigh measurements might be an equally good indicator. But Dr. Ian Scott of Princess Alexandra Hospital in Brisbane, Australia, disagreed, saying the statistics in the Danish study were too limited.

He said larger studies would need to be done before doctors could decide that thigh measurement was any kind of good predictor of health.

“It seems unlikely that thigh circumference will be clinically useful,” Scott wrote in a commentary.

Tim Olds, a professor of Health Sciences at the University of South Australia, saw some value in the study, however.

“This is a very interesting line of research, because it would suggest that interventions which protect or increase muscle mass (such as weight training) may be effective in reducing cardiovascular disease even if no loss of body fat occurs,” Olds said in a statement.

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