Category Archives: Disease

Disease

Researchers find prostate cancer stem cell

Researchers find prostate cancer stem cell

Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. CSCs are therefore tumorigenic (tumor-forming), perhaps in contrast to other non-tumorigenic cancer cells. CSCs may generate tumors through the stem cell processes of self-renewal and differentiation into multiple cell types. Such cells are proposed to persist in tumors as a distinct population and cause relapse and metastasis by giving rise to new tumors. Therefore, development of specific therapies targeted at CSCs holds hope for improvement of survival and quality of life of cancer patients, especially for sufferers of metastatic disease.

Existing cancer treatments have mostly been developed based on animal models, where therapies able to promote tumor shrinkage were deemed effective. However, animals could not provide a complete model of human disease. In particular, in mice, whose life spans do not exceed two years, tumor relapse is exceptionally difficult to study.

The efficacy of cancer treatments is, in the initial stages of testing, often measured by the ablation fraction of tumor mass (fractional kill). As CSCs would form a very small proportion of the tumor, this may not necessarily select for drugs that act specifically on the stem cells. The theory suggests that conventional chemotherapies kill differentiated or differentiating cells, which form the bulk of the tumor but are unable to generate new cells. A population of CSCs, which gave rise to it, could remain untouched and cause a relapse of the disease.

Researchers have found a stem cell, a kind of master cell, that may cause at least some types of prostate cancer.

Their findings are only experimental — the stem cells were found in mice — but could explain at least some types of prostate cancer and eventually offer new ways to treat it, they reported on Wednesday in the journal Nature.

The findings also show a potential new source for prostate tumors — so-called luminal cells, which secrete various compounds used in the prostate.

“The role of stem cells in the development of prostate cancer has been a focus of speculation for many years,” Dr. Helen Rippon of Britain’s Prostate Cancer Charity said in a statement.

“Importantly, this new stem cell does not rely on androgens — the male sex hormones that control prostate growth — to survive and grow. This may give a clue as to why prostate cancer often becomes resistant to treatments designed to regulate these androgens in the later stages of the disease,” added Rippon, who was not involved in the research.

“This improved knowledge will also be a step forward in learning how we might help to prevent the disease from developing in men in the first place.”

Michael Shen of Columbia University Medical Center and colleagues named the new stem cells CARNs, for castration-resistant Nkx3.1-expressing cells.

They normally regenerate part of the tissue that lines the inside of the gland, which produces semen. But the cells can also form tumors if certain genes meant to stop out-of-control growth get turned off.

Shen said researchers had believed that tumors arise from a different layer of cells in the prostate, called basal cells.

“Previous research suggested that prostate cancer originates from basal stem cells, and that during cancer formation these cells differentiate into luminal cells,” Shen said in a statement. “Instead, CARNs may represent a luminal origin for prostate cancer.”

Prostate cancer is the second most common cancer in men worldwide after lung cancer, killing 254,000 men a year globally.

prostate cancer stem, prostate cancer stem Health, prostate cancer stem Health Latest, prostate cancer stem Health Information, prostate cancer stem Health information, prostate cancer stemHealth Photo,Exercising for Weight Health photo, prostate cancer stem Health Latest, prostate cancer stemHealth latest, Exercising for Weight Health Story, Healthy Minnesota Health story, prostate cancer stem Video, prostate cancer stem video, prostate cancer stem Health History, prostate cancer stem Health history, prostate cancer stemover Picture, history, prostate cancer stem Asia, Healthy Minnesota asia, prostate cancer stem Gallery, Exercising for Weight gallery, prostate cancer stem Photo Gallery, Healthy Minnesota photo gallery, prostate cancer stem Picture, prostate cancer stem picture, prostate cancer stem Web, Malaysia Health, web Health, web Health picture, video photo, video surgery, gallery, laparoscopy, virus, flu, drug, video, Health Health, calories, photo, nutrition, health video, symptoms, cancer, medical, beating, diet, physical, Training, organic, gym, blister, exercise, weightloss, surgery, spiritual, eating, tips, skin, operation, bf1, prostate, cancer, stem

Clean Hands Help Prevent the Flu

October 21, 2013Fluand, be, bealthy breakfast information, bf1, can, CDC, CDCstreaminghealth, Clean Hands, Clean Hands Asia, Clean Hands Gallery, Clean Hands Health, Clean Hands Health Latest, Clean Hands Help Prevent, Clean Hands Help Prevent Flu, Clean Hands History, Clean Hands Information, Clean Hands Latest, Clean Hands Photo, Clean Hands Photo Gallery, Clean Hands Picture, Clean Hands Story, Clean Hands Video, Clean Hands Web, Drug, ehealth, Flu, flu viruses, gallery, gejala, H1N1, history, home, in, infectious diseases, Influenza, is, Malaysia Health, media, media id, of, on, one, operation, or, Pandemic, photo, picture, podcast, social, SwineFlu, to, use, video, video photo, virus, way, web Health, yourazuan

Clean Hands Help Prevent the Flu

[media id=11 width=500 height=400]

Clean hands can help prevent the spread of infectious diseases, such as flu. This podcast explains the proper way to wash your hands.

CDC has reported that the spread of H1N1 influenza A (swine) virus is thought to be happening in the same way that seasonal flu spreads.

Flu viruses are spread mainly from person to person through coughing or sneezing of people with influenza. Sometimes people may become infected by touching something with flu viruses on it and then touching their mouth or nose.

There are several simple precautions CDC recommends everyone practice in order to stay healthy:

Cover your nose and mouth with a tissue when you cough or sneeze. Throw the tissue in the trash after you use it.

Stay home from work or school if you get sick and limit contact with others to keep from infecting them.

Wash your hands often with soap and water, especially after you cough or sneeze. Alcohol-based hand cleansers are also effective.

Education is a critical component of managing the risk of flu transmission. All members of the family should be educated on simple methods to limit the spread of potential infection in their household. Using an antiseptic product like Betadine® Skin Cleanser is one example. Povidone-iodine, the active ingredient in Betadine® Surgical Scrub and Skin Cleanser products, can help reduce germs on the skin that can potentially cause infections. Betadine products are for external use only and should not be used for longer than one week unless directed by your doctor.

Clean Hands, Clean Hands Health, Clean Hands Health Latest, Clean Hands Information, bealthy breakfast information, Clean Hands Photo, Clean Hands Latest, Clean Hands latest, Clean Hands Story, Clean Hands story, Clean Hands Video, Clean Hands video, Clean Hands History, Clean Hands history, history, Clean Hands Asia, Clean Hands asia, Clean Hands Gallery, Clean Hands gallery, Clean Hands Photo Gallery, Clean Hands photo gallery, Clean Hands Picture, Clean Hands picture, Clean Hands Web, Malaysia Health, web Health ,picture, video photo, virus, flu, drug, gejala, video, photo, operation, bf1, SwineFlu, Flu, Influenza, Pandemic, Flu, CDC, CDCstreaminghealth, ehealth, social, media, H1N1

Prostate cancer screening: More harm than good?

October 20, 2013Cancerand, antigen, atomic physics, be, beating, bf1, blister, blood test, calories, Cancer, cancer screening, cancers, diet, double edged sword, Drug, eating, electromagnetic fields, electromagnetic shielding, electron shells, Exercise, Exercising for Weight Gallery, Exercising for Weight Health Story, Exercising for Weight Health Photo, Exercising Weight, Flu, for, gallery, good, Health Health, Health Latest, health video, Healthy Minnesota, Healthy Minnesota Asia, Healthy Minnesota Health Story, Healthy Minnesota Photo Gallery, history, ill effects, in, is, laparoscopy, majority of men, Malaysia Health, medical, metal detector, million, Nutrition, of, operation, or, organic, paper pulp, photo, physics and chemistry, picture, process that represents lighter shades, Prostate, Prostate cancer, Prostate cancer Asia, Prostate cancer Gallery, Prostate cancer Health, Prostate cancer Health History, Prostate cancer Health Information, Prostate cancer Health Latest, Prostate cancer Photo Gallery, Prostate cancer Picture, Prostate cancer Video, Prostate cancer Web, Prostate cancer Health Photo, Prostate cancer over Picture, prostate cancer screening, psa, routine screening, screening, skin, spiritual, Surgery, symptoms, tiny dots, tips, to, treatment, video, video photo, video surgery, virus, web Health, weightloss, x rayazuan

Prostate cancer screening: More harm than good?

One meaning of screening is the investigation of a great number of something (for instance, people) looking for those with a particular problem or feature. For example at an airport many bags are screened by x-ray to try to detect any which may contain weapons or explosives, and people are screened by passing through a metal detector. If only part of a population is screened, screening is equivalent to sampling in statistics.

Screening can also mean preventing access of something by some sort of barrier. Particular cases:

Electromagnetic shielding in physics, the exclusion of electric, magnetic, or electromagnetic fields by a metallic screen or shield

In atomic physics and chemistry, the screening effect or atomic shielding is the reduction of effective nuclearcharge by intervening electron shells

Screening (printing), a process that represents lighter shades as tiny dots, rather than solid areas, of ink by passing ink through a perforated screen

The investigation of a large population is related; the members of a population are filtered by a metaphorical, rather than physical, screen

Screening is a process stage when cleaning paper pulp

Routine screening for prostate cancer has resulted in more than 1 million U.S. men being diagnosed with tumors who might otherwise have suffered no ill effects from them, U.S. researchers said on Monday.

They said prostate cancer screening is a double-edged sword, catching serious cancers in a few but causing needless worry and expense for the majority of men, who may be getting treatment for tumors growing too slowly to do any harm.

The team looked to see how many additional men have been diagnosed with prostate cancer since the introduction in 1986 of a widely used blood test for prostate cancer that looked for a prostate-cancer specific antigen, or PSA.

“Our estimate is that number is about 1.3 million people in the United States. That is a huge effect,” said Dr. H. Gilbert Welch of the VA Outcomes Group in White River Junction, Vermont, whose study appears in the Journal of the National Cancer Institute.

More than 1 million of those were treated, they found.

“These are men who could not be helped by treatment because their cancer was not destined to cause them symptoms or death,” Welch said in a telephone interview.

The increased diagnosis rate more than tripled in men aged 50 to 59 and increased more than a sevenfold in men under age 50.

And while prostate cancer deaths have declined since the introduction of PSA testing, Welch said about 20 men had to be diagnosed and treated for every one who benefited.

Prostate cancer , Prostate cancer Health, Prostate cancer Health Latest, Prostate cancer Health Information, Prostate cancer Health information, Prostate cancer Health Photo,Exercising for Weight Health photo, Prostate cancer Health Latest, Prostate cancer Health latest, Exercising for Weight Health Story, Healthy Minnesota Health story, Prostate cancer Video, Prostate cancer video, Prostate cancer Health History, Prostate cancer Health history, Prostate cancer over Picture, history, Prostate cancer Asia, Healthy Minnesota asia, Prostate cancer Gallery, Exercising for Weight gallery, Prostate cancer Photo Gallery, Healthy Minnesota photo gallery, Prostate cancer Picture, Prostate cancer picture, Prostate cancer Web, Malaysia Health, web Health, picture, video photo, video surgery, gallery, laparoscopy, virus, flu, drug, video, Health Health, calories, photo, nutrition, health video, symptoms, cancer, medical, beating, diet, organic, blister, exercise, weightloss, surgery, spiritual, eating, tips, skin, operation, bf1, Prostate, cancer, screening