Breast cancer patients have low vitamin D levels

In a study of 166 women undergoing treatment for breast cancer, nearly 70 percent had low levels of vitamin D in their blood, according to the study presented at the American Society of Clinical Oncology’s Breast Cancer Symposium in San Francisco.

The analysis showed women with late-stage disease and non-Caucasian women had even lower levels.

“Vitamin D is essential to maintaining bone health, and women with breast cancer have accelerated bone loss due to the nature of hormone therapy and chemotherapy. It’s important for women and their doctors to work together to boost their vitamin D intake,” said Luke Peppone, Ph.D., research assistant professor of Radiation Oncology, at Rochester’s James P. Wilmot Cancer Center.

Scientists funded by the NCI analyzed vitamin D levels in each woman, and the average level was 27 nanograms per milliliter; more than two-thirds of the women had vitamin deficiency. Weekly supplementation with high doses of vitamin D — 50,000 international units or more — improved the levels, according to Peppone’s study.

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Pomegranate compounds may ease breast cancer risk

Enzyme-blocking chemicals in pomegranates may reduce the risk of estrogen-fueled breast cancers, U.S. researchers said on Tuesday.

An acid found in pomegranates appears to block aromatase, an enzyme that converts androgen to estrogen, a hormone that plays a role in the development of breast cancer, the researchers wrote in the journal Cancer Prevention Research.

“We identified some of these chemicals in pomegranates that actually have properties that can suppress aromatase,” researcher Shiuan Chen, of the City of Hope cancer research and treatment center in Duarte, California, said in a telephone interview.

Many women who have had breast cancer take medicines called aromatase inhibitors — such as Pfizer’s Aromasin, Novartis’ Femara and AstraZeneca Plc’s Arimidex — to keep estrogen from feeding tumors.

Chen and colleagues studied whether compounds, or phytochemicals, in pomegranates can suppress aromatase and ultimately block cancer growth. They found that 10 natural compounds in the fruit may potentially prevent estrogen-related breast cancer.

Chen said the compounds would not be a replacement for aromatase inhibitors.

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Breast cancer patients have low vitamin D levels

Breast cancer patients have low vitamin D levels

Pomegranate compounds may ease breast cancer risk

Pomegranate compounds may ease breast cancer risk