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Eggs for making H1N1 vaccine meet world standards

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Eggs for making H1N1 vaccine meet world standards

An egg is a round or oval body laid by the female of any number of different species, consisting of an ovum surrounded by layers of membranes and an outer casing, which acts to nourish and protect a developing embryo and its nutrient reserves. Most edible eggs, including bird eggs and turtle eggs, consist of a protective, oval eggshell, the albumen (egg white), the vitellus (egg yolk), and various thin membranes. Every part is edible, although the eggshell is generally discarded. Eggs are considered a good source of protein and choline. Because of this, the egg falls in the Meats category under the Food Guide Pyramid.

Roe and caviar are edible eggs produced by fish.

The eggs provided by two local companies to be used in the manufacture of H1N1 vaccine by Adimmune Corp. meet both world and local standards, the Central Epidemic Command Center under the Cabinet-level Department of Health (DOH) said Wednesday.”The eggs being used by Adimmune to produce HINI vaccine scrupulously meet the international standards set forth by the World Health Organization (WHO) and by Good Manufacturing Practice (GMP) criteria imposed by the DOH for high-quality food, ” the center said in response to a report by Next Magazine that questioned the safety of the eggs used by Taiwan’s sole human vaccine manufacturer.

Chen Hui-fang, director-general of the Bureau of Pharmaceutical Affairs under the DOH, said that in line with WHO guidelines, embryo eggs used to make vaccine must come from healthy chickens of adequate maturity and that such eggs supplied by two local providers fully meet the WHO regulations.

Eggs produced by chickens in the two enclosed farms are being raised in a fully automated and safe environment with round-the-clock monitoring, Chen said.

According to Chen, the bureau dispatched officials to inspect the production operations for the embryo eggs late last month, and no bacteria or residue from antibiotics or hormones were detected.

A day earlier, an Adimmune executive said the company’s vaccine production had entered the “filling stage,” which means that the dose of the vaccine has largely been established.

The executive added that the company is expected to launch human clinical trials in two weeks, to be conducted at the National Taiwan University (NTU) Hospital, the Tri-Service General Hospital and the Taipei Medical University-Wan Fang Hospital.

The company is recruiting 250 adults and 150 children to take part in the trials, he noted.

Immunizations are expected to begin in late October, with healthcare workers, pregnant women and children between 6 months and 6 years selected as priority recipients.

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Study finds potential way to make an AIDS vaccine

in.reuters.com

Study finds potential way to make an AIDS vaccine

The discovery of immune system particles that attack the AIDS virus may finally open a way to make a vaccine that could protect people against the deadly and incurable infection, U.S. researchers said on Thursday.

They used new technology to troll through the blood of 1,800 people infected with the AIDS virus and identified two immune system compounds called antibodies that could neutralize the virus.

And they found a new part of the virus that the antibodies attack, offering a new way to design a vaccine, they reported in the journal Science.

“So now we may have a better chance of designing a vaccine that will elicit such broadly neutralizing antibodies, which we think are key to successful vaccine development,” said Dennis Burton of The Scripps Research Institute in La Jolla, California, who led the study.

“The findings themselves are an exciting advance toward the goal of an effective AIDS vaccine because now we’ve got a new, potentially better target on HIV to focus our efforts for vaccine design,” added Wayne Koff of the International AIDS Vaccine Initiative, or IAVI, which sponsored the study.

Since the AIDS pandemic started in the early 1980s, more than 25 million people globally have died from the virus. The World Health Organization estimates that 33 million are currently infected.

There is no cure, although a cocktail of drugs can help keep the virus under control. Efforts to make a vaccine have failed almost completely.

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