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Studies show one dose of H1N1 vaccine may be enough

June 27, 2012Uncategorizedasia studies, be, beating, bf1, blister, calories, Cancer, diet, dose, Drug, eating, enough, Exercise, Exercising for Weight Gallery, Exercising for Weight Health Story, Exercising for Weight Health Photo, Flu, flu drug, gallery, Gym, H1N1, Health Health, health history, health story, health studies, health video, health web, Healthy Minnesota, Healthy Minnesota Asia, Healthy Minnesota Health Story, Healthy Minnesota Photo Gallery, history, history studies, in, information studies, laparoscopy, Malaysia Health, may, medical, million, minnesota health, Nutrition, nutrition health, of, one, operation, organic, photo, photo studies, physical, show, skin, spiritual, Studies, Studies show, Studies show Asia, Studies show Gallery, Studies show Health, Studies show Health History, Studies show Health Information, Studies show Health Latest, Studies show Photo Gallery, Studies show Picture, Studies show Video, Studies show Web, Studies show Health Photo, Studies show over Picture, Surgery, swine flu, symptoms, tips, to, training, vaccine, video, video health, video photo, video studies, video surgery, virus, web Health, web Health picture, weight health, weightlossazuan

Studies show one dose of H1N1 vaccine may be enough

Two studies published on Thursday confirmed that a single dose of swine flu vaccine can protect people from the new pandemic H1N1 virus — welcome news to global health officials who had worried that people might need two doses.

Australian vaccine maker CSL Inc. released new data showing its vaccine got what would be considered a protective immune response with a singe dose, and Swiss drug maker Novartis presented a study confirming a report from last week showing its vaccine worked at an even lower dose when boosted with an immune system compound called an adjuvant.

Both studies, published in the New England Journal of Medicine, may lay to rest fears about the logistical nightmare of trying to vaccinate hundreds of millions of people globally with two doses of H1N1 vaccine — given a month apart — in addition to a single recommended dose of seasonal influenza vaccine.

Last week China’s Sinovac also reported its vaccine protected patients with a single dose.

The new H1N1 strain of flu, declared a pandemic in June, could eventually infect one third of the world’s population, or 2 billion people, according to the World Health Organization.

Because it is a new strain, infectious disease experts had said people would likely need two doses to get full immunity against the virus. They are rushing to put in place vaccine programs as the weather cools in the Northern Hemisphere and the traditional flu season starts.

About 20 pharmaceutical companies including Sanofi-Aventis, GlaxoSmithKline and AstraZeneca’s MedImmune unit are also racing to develop H1N1 vaccine as governments scramble to secure supplies.

The United States hopes to vaccinate 160 million Americans by the beginning of December.

NASAL SPRAY READY

Also on Thursday, MedImmune said its inhaled vaccine against the pandemic H1N1 virus could be ready to start shipping to the U.S. government by the end of September.

MedImmune’s Dr. Raburn Mallory said the company has submitted safety data for its nasal spray swine flu vaccine to the U.S. Food and Drug Administration.

“There are no red flags there. We think we can have 5 million doses ready to distribute at the end of September,” Mallory said in an interview. U.S. officials had not expected vaccination to begin until mid-October.

The company has 5 million doses in spray devices now, a company spokeswoman said, adding that a more conservative estimate would be that 3.5 million doses could be sent out by the end of September.

U.S. health officials said they started testing swine flu vaccines in pregnant women this week and were scheduled on Friday to report on results of some of the tests being done on various swine flu vaccines for the U.S. market.

The U.S. Food and Drug Administration is licensing H1N1 vaccines as if they are a simple reformulation of the seasonal flu vaccine. This does not require clinical tests, but the National Institutes of Health is running clinical tests anyway, to be sure it is safe and to find the best dose.

Governments in Europe have started to take delivery of H1N1 swine flu vaccines but are awaiting a license from European authorities before they can start mass vaccinations.

“The immune response to all these vaccines is a very high response, whatever type of vaccine it is, whether it is adjuvanted or non-adjuvanted,” Thomas Lonngren, executive director of the European Medicines Agency or EMEA, told a news briefing.

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Eggs for making H1N1 vaccine meet world standards

June 27, 2012Uncategorizedalbumen, and, beating, bf1, bird eggs, blister, cabinet level, calories, Cancer, chen hui, diet, DOH, Drug, eating, egg, egg white, egg yolk, Eggs, Eggs Asia, Eggs Gallery, Eggs Health, Eggs Health History, Eggs Health Information, Eggs Health Latest, Eggs Photo Gallery, Eggs Picture, Eggs Video, Eggs Web, EggsHealth latest, EggsHealth Photo, Eggsover Picture, Exercise, Exercising for Weight Gallery, Exercising for Weight Health Story, Exercising for Weight Health Photo, Exercising Weight, Flu, food guide pyramid, for, gallery, good manufacturing practice, Gym, H1N1, Health Health, health video, Healthy Minnesota Asia, Healthy Minnesota Health Story, Healthy Minnesota Photo Gallery, history, hui fang, human vaccine, in, is, laparoscopy, making, Malaysia Health, medical, meet, next magazine, nutrient reserves, Nutrition, of, operation, organic, oval body, photo, physical, production operations, quality food, skin, spiritual, standards, Surgery, symptoms, thin membranes, tips, to, training, turtle eggs, two local companies, vaccine, vaccine manufacturer, video, video photo, video surgery, virus, web Health, web Health picture, weightloss, world, world health organizationazuan

Eggs for making H1N1 vaccine meet world standards

An egg is a round or oval body laid by the female of any number of different species, consisting of an ovum surrounded by layers of membranes and an outer casing, which acts to nourish and protect a developing embryo and its nutrient reserves. Most edible eggs, including bird eggs and turtle eggs, consist of a protective, oval eggshell, the albumen (egg white), the vitellus (egg yolk), and various thin membranes. Every part is edible, although the eggshell is generally discarded. Eggs are considered a good source of protein and choline. Because of this, the egg falls in the Meats category under the Food Guide Pyramid.

Roe and caviar are edible eggs produced by fish.

The eggs provided by two local companies to be used in the manufacture of H1N1 vaccine by Adimmune Corp. meet both world and local standards, the Central Epidemic Command Center under the Cabinet-level Department of Health (DOH) said Wednesday.”The eggs being used by Adimmune to produce HINI vaccine scrupulously meet the international standards set forth by the World Health Organization (WHO) and by Good Manufacturing Practice (GMP) criteria imposed by the DOH for high-quality food, ” the center said in response to a report by Next Magazine that questioned the safety of the eggs used by Taiwan’s sole human vaccine manufacturer.

Chen Hui-fang, director-general of the Bureau of Pharmaceutical Affairs under the DOH, said that in line with WHO guidelines, embryo eggs used to make vaccine must come from healthy chickens of adequate maturity and that such eggs supplied by two local providers fully meet the WHO regulations.

Eggs produced by chickens in the two enclosed farms are being raised in a fully automated and safe environment with round-the-clock monitoring, Chen said.

According to Chen, the bureau dispatched officials to inspect the production operations for the embryo eggs late last month, and no bacteria or residue from antibiotics or hormones were detected.

A day earlier, an Adimmune executive said the company’s vaccine production had entered the “filling stage,” which means that the dose of the vaccine has largely been established.

The executive added that the company is expected to launch human clinical trials in two weeks, to be conducted at the National Taiwan University (NTU) Hospital, the Tri-Service General Hospital and the Taipei Medical University-Wan Fang Hospital.

The company is recruiting 250 adults and 150 children to take part in the trials, he noted.

Immunizations are expected to begin in late October, with healthcare workers, pregnant women and children between 6 months and 6 years selected as priority recipients.

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Vaccines could halve sickle-cell deaths in Africa

June 26, 2012UncategorizedAfrica, and, anemia, bacterial infection, bacterial infections, beating, bf1, blister, blood, blood flow, calories, Cancer, cell anemia, children, could, deaths, developed countries, diet, Drug, eating, Exercise, Exercising for Weight Gallery, Exercising for Weight Health Story, Exercising for Weight Health Photo, Exercising Weight, Flu, for, gallery, genetic disease, Gym, halve, Health Health, health video, Healthy Minnesota, Healthy Minnesota Asia, Healthy Minnesota Health Story, Healthy Minnesota Photo Gallery, history, in, is, kemri, kenya medical research institute, lancet medical journal, laparoscopy, Malaysia Health, medical, medical research institute, Nutrition, of, operation, organ damage, organic, photo, physical, red blood cells, sickle shape, sickle-cell, skin, spiritual, Surgery, symptoms, tips, to, training, tropical diseases, trust program, vaccination, vaccine, Vaccines, Vaccines Asia, Vaccines Gallery, Vaccines Health, Vaccines Health History, Vaccines Health Information, Vaccines Health Latest, Vaccines Photo Gallery, Vaccines Picture, Vaccines Video, Vaccines Web, VaccinesHealth latest, VaccinesHealth Photo, Vaccinesover Picture, video, video photo, video surgery, virus, vulnerability, web Health, web Health picture, weightloss, wellcome trustazuan

Vaccines could halve sickle-cell deaths in Africa

Vaccination against bacterial infections using vaccines readily available in developed countries could save the lives of thousands of children with sickle-cell anemia in Africa, researchers said on Thursday.

Tom Williams, an expert in tropical diseases from the Kenya Medical Research Institute (KEMRI), said 90 percent of children born with sickle-cell anemia in Africa die before they are diagnosed and can get treatment, and half of those lives could be saved if sufferers were protected from bacterial infections.

“The problem here in Africa is that there is hardly anyone doing any screening,” Williams said. “So, as a result, most of the children in Africa who are born with sickle-cell anemia are dead before they are even diagnosed.”

Experts estimate that sickle-cell anemia kills more children in Africa than HIV, Williams said, but while HIV commands vast attention from the international community sickle-cell anemia is “virtually invisible.”

In a study conducted in rural Kenya and published in the Lancet medical journal, Williams and colleagues at the KEMRI/Wellcome Trust program in Kilifi screened almost 40,000 admissions to hospital and identified 2,000 cases of bacterial infection.

While in the general population fewer than three in 1,000 children were found to have sickle cell anemia, this figure increased more than 20-fold — to more than 60 per 1,000 — for children admitted to hospital with bacterial infections.

Sickle-cell anemia affects millions of people worldwide, but more than 80 percent of cases are in Africa, where around 200,000 children are born with the disease every year.

It is a genetic disease in which red blood cells deform into a sickle shape and cluster, blocking blood flow and causing pain, vulnerability to infections and organ damage.

The findings confirm that, just as in richer nations, African children with sickle-cell anemia are at huge risk of bacterial infections because the disease hampers blood flow and causes episodes of acute anemia, Williams said.

The most common causes of bacterial infection among children with sickle-cell were Streptococcus pneumoniae (41 percent of cases) and Haemophilus influenzae type b (12 percent of cases).

Vaccines against both — a pneumococcal vaccine and another called Hib — are given routinely in the United States and Europe, but have been slow getting to Africa because funds have largely been focused on other priorities.

Dan Thomas of the Global Alliance for Vaccines and Immunization (GAVI) in Geneva, said his group provides the Hib vaccine, which is made by a range of drug companies, to 35 African nations as part of a 5-in-1 shot.

GAVI has also introduced a pneumococcal vaccine made by Wyeth, a U.S. drug company which is being bought by Pfizer, to Rwanda and Gambia, and is “working on rolling an improved pneumococcal vaccine out across Africa in the next few years,” he said.

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