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Program eases trauma of chemotherapy side effects

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Program eases trauma of chemotherapy side effects

When Michele VonGerichten started chemotherapy to treat her breast cancer, one of her big worries was that her newly bald head would distract attention as she tried to carry on with her marketing job.

“It was just devastating to me, the thought of losing my hair,” said the marketing and public relations executive for a boat manufacturer in Florida.

“I have to meet with customers and dealers. And with my co-workers … I wanted to make sure they were going to be looking at me and focusing on me, and focusing on what I was helping them with … and not staring at my head, or looking at my face and asking ‘Why do you look so different?'”

VonGerichten found help from Look Good … Feel Better, a national public service program that helps women cope with the appearance-related side effects of cancer treatment.

Like 1 million other people around the world who have taken part in the free program over the last 20 years, VonGerichten received a kit of makeup and took part in a two-hour group workshop given by a volunteer beauty professional.

“There were women of all ages … . They were all in various times of their treatment,” she said. “But it just felt like, OK I’m not alone here, there are other women going through this.”

Look Good … Feel Better is a collaboration between the American Cancer Society and the Personal Care Products Council Foundation — the charitable arm of the $250 billion personal care industry’s main trade association.

Executive Director Louanne Roark said the program began after a doctor asked the former president of the Personal Care Products Council to help one of his cancer patients who was so self-conscious about the side effects of her treatment that she would not leave her hospital room.

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Stressful childhood may mean earlier death

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Stressful childhood may mean earlier death

Having a stressful childhood may slash decades off a person’s life, researchers from the Centers for Disease Control and Prevention (CDC) report.

Among people who reported experiencing at least six of eight different bad childhood experiences-from frequent verbal abuse to living with a mentally ill person-average age at death was about 61, compared to 79 for people who didn’t have any of these experiences as children, the researchers found.

Dr. David W. Brown and Dr. Robert Anda of the CDC and colleagues from the CDC and Kaiser Permanente have been following 17,337 men and women who visited the health plan between 1995 and 1997 to investigate the relationship between bad childhood experiences and health.

So far, Anda noted in an interview, they have shown links between childhood stressors and heart disease, lung disease, liver disease and other conditions. “The strength of it really surprised me, how powerfully it’s related to health,” the researcher said.

In the current analysis, the researchers reviewed death records through 2006 to investigate whether these experiences might also relate to mortality. During that time, 1,539 study participants died.

Each person was asked whether they had any of eight different categories of such experiences, including verbal abuse, physical abuse, sexual abuse with physical contact, having a battered mother, having a substance-abusing person in the household, having a mentally ill person in the household, having a household member who was incarcerated, or having one’s parents separate or divorce.

Sixty-nine percent of the study participants who were younger than 65 reported at least one of the adverse childhood experiences, while 53 percent of people 65 and older did.

Those who reporting experiencing six or more were 1.5 times more likely to die during follow-up than those who reported none, the researchers found. They were 1.7 times as likely to die at age 75 or younger, and nearly 2.4 times as likely to die at or before age 65.

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Studies show one dose of H1N1 vaccine may be enough

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Studies show one dose of H1N1 vaccine may be enough

Two studies published on Thursday confirmed that a single dose of swine flu vaccine can protect people from the new pandemic H1N1 virus — welcome news to global health officials who had worried that people might need two doses.

Australian vaccine maker CSL Inc. released new data showing its vaccine got what would be considered a protective immune response with a singe dose, and Swiss drug maker Novartis presented a study confirming a report from last week showing its vaccine worked at an even lower dose when boosted with an immune system compound called an adjuvant.

Both studies, published in the New England Journal of Medicine, may lay to rest fears about the logistical nightmare of trying to vaccinate hundreds of millions of people globally with two doses of H1N1 vaccine — given a month apart — in addition to a single recommended dose of seasonal influenza vaccine.

Last week China’s Sinovac also reported its vaccine protected patients with a single dose.

The new H1N1 strain of flu, declared a pandemic in June, could eventually infect one third of the world’s population, or 2 billion people, according to the World Health Organization.

Because it is a new strain, infectious disease experts had said people would likely need two doses to get full immunity against the virus. They are rushing to put in place vaccine programs as the weather cools in the Northern Hemisphere and the traditional flu season starts.

About 20 pharmaceutical companies including Sanofi-Aventis, GlaxoSmithKline and AstraZeneca’s MedImmune unit are also racing to develop H1N1 vaccine as governments scramble to secure supplies.

The United States hopes to vaccinate 160 million Americans by the beginning of December.

NASAL SPRAY READY

Also on Thursday, MedImmune said its inhaled vaccine against the pandemic H1N1 virus could be ready to start shipping to the U.S. government by the end of September.

MedImmune’s Dr. Raburn Mallory said the company has submitted safety data for its nasal spray swine flu vaccine to the U.S. Food and Drug Administration.

“There are no red flags there. We think we can have 5 million doses ready to distribute at the end of September,” Mallory said in an interview. U.S. officials had not expected vaccination to begin until mid-October.

The company has 5 million doses in spray devices now, a company spokeswoman said, adding that a more conservative estimate would be that 3.5 million doses could be sent out by the end of September.

U.S. health officials said they started testing swine flu vaccines in pregnant women this week and were scheduled on Friday to report on results of some of the tests being done on various swine flu vaccines for the U.S. market.

The U.S. Food and Drug Administration is licensing H1N1 vaccines as if they are a simple reformulation of the seasonal flu vaccine. This does not require clinical tests, but the National Institutes of Health is running clinical tests anyway, to be sure it is safe and to find the best dose.

Governments in Europe have started to take delivery of H1N1 swine flu vaccines but are awaiting a license from European authorities before they can start mass vaccinations.

“The immune response to all these vaccines is a very high response, whatever type of vaccine it is, whether it is adjuvanted or non-adjuvanted,” Thomas Lonngren, executive director of the European Medicines Agency or EMEA, told a news briefing.

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