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Swine flu vaccine due next week in Pa., N.J.

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Swine flu vaccine due next week in Pa., N.J.

After months of anticipation, the first doses of swine flu vaccine are expected to arrive next week, public health officials said yesterday as the federal government began accepting orders from the states.

In Pennsylvania, they will go to healthy children ages 5 to 9 in just three regions of the state, including the southeast. New Jersey will direct a smaller number of doses to ages 2 through 24 statewide.

The priority lists are likely to change weekly, if not daily, as the federal government ramps up the biggest vaccination campaign it has ever attempted.

Pregnant women, for example, are among those at highest risk from the disease – but the first doses, in a nasal spray, will be a form of live virus that isn’t safe for them. Shots made with an inactivated or “dead” virus should arrive a week or so later.

The live virus is safe for children without underlying medical conditions. Children are the most likely of all age groups to catch and spread the new flu. While most people will require one dose, children under 10 will need two, nearly a month apart, to trigger a robust immune response. (The same applies to children getting seasonal flu vaccine for the first time.) So children will get first dibs.

“Targeting the healthy and the young is a good way to get this vaccine out quickly to a significant population,” said Susan Walsh, a deputy state health commissioner in New Jersey.

Where to get the vaccine?

Officials in both states urged parents to call their pediatricians, although they are not likely to know that they will have the vaccine until it actually arrives. Many schools, including those in Philadelphia, will hold vaccination clinics; letters and permission forms will go out to parents beforehand.

Health department Web sites for New Jersey, Pennsylvania, and Philadelphia – the three local overseers for swine flu vaccination – will list locations when more doses become available, officials said. All vaccinations are voluntary.

Because the swine flu vaccine was purchased entirely by the federal government, providers can charge only an administration fee, and many will offer it free. It generally will not be available from supermarkets and pharmacies that run clinics for seasonal vaccine.

Swine flu was more common than the seasonal strains in the southern hemisphere, which experienced a full influenza season after the novel H1N1 first appeared in Mexico and the United States in April.

That has led to scattered reports in the north that the seasonal vaccine would be unnecessary. Public health officials strongly disagreed.

“We have no idea what the interplay is going to be between [swine] flu and the seasonal flu,” said Stephen Ostroff, Pennsylvania’s acting physician general.

Those seeking to cover all their bases might also want to consider a report from the U.S. Centers for Disease Control and Prevention yesterday saying that, as in previous flu pandemics, bacterial pneumonia contributed to some swine flu deaths in spring and summer.

Pneumococcal vaccine is in plentiful supply, as is seasonal flu vaccine.

But no one knows how many people will want them, let alone the new swine flu vaccine. Just 35 percent of adults in New Jersey and 38 percent in Pennsylvania said they got the seasonal flu vaccine last year, according to the most recent federal survey.

And a Consumer Reports poll released yesterday found that just 35 percent of parents said they definitely would have their children vaccinated for swine flu.

“Who wants it? Who knows?” said Caroline Johnson, director of the division of disease control for the Philadelphia Department of Public Health.

Despite the newness of the vaccine, public health officials say they have no safety concerns. It is essentially the “seasonal vaccine with a different strain contained in it,” said Ostroff.

The first-to-arrive spray form of the vaccine contains no thimerosal – a preservative that some people believe is linked to other diseases – and later versions will be available both with or without it, officials said.

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Canada outranks U.S. in healthcare report card

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Canada outranks U.S. in healthcare report card

Canada outperforms the United States in health outcomes but is well behind global leaders like Japan in overall health of its population, a Canadian report released on Monday showed.

The annual report card by the Conference Board of Canada ranked Canada 10th out of 16 developed countries, with a “B” grade. The United States was the worst performer, placing 16th and earning a “D” grade.

“Canada has been at the center of much of the debate on U.S. health care reform. Since Canada ranks ahead of the United States on all but one indicator of health status … it is clear that we are getting better results,” Gabriela Prada, director of health policy at the Conference Board, said in a statement.

“But when we look beyond the narrow Canada-U.S. comparison to the rest of the world, Canadians rank in the middle of the pack in terms of their health status,” Prada said.

Most of the data on which the report card was based is from 2006, the group said.

President Barack Obama has pledged to reform the country’s healthcare system, which is expensive and leaves millions of Americans without coverage. Canada, with its single-payer government-run system, is often held out as an example to be praised or derided by U.S. critics.

The Conference Board, which has been issuing the report card since 1996, ranked the 16 countries according to 11 criteria, including life expectancy, mortality due to cancer, circulatory diseases, respiratory diseases, metal disorders, as well as infant mortality and self-reported health status.

Japan was once again the top-ranking country. Switzerland, Italy, and Norway also earned “A” grades.

“B” grades were given to Sweden, France, Finland, Germany, Australia and Canada, while Netherlands, Austria and Ireland earned a “C” grade, the report showed.

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Skin cancer can be inherited: studies

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Skin cancer can be inherited: studies

One found that having an identical twin with melanoma increased a person’s own risk of developing the disease much more than having a fraternal twin with this type of skin cancer. The other found that having a sibling or parent with one of several different types of non-melanoma skin cancer increased risk as well.

Several studies have suggested melanoma and other skin cancers run in families, but it can be difficult to tease out the difference between the influence of genes and environment. In the Australian study, Dr. Sri N. Shekar of the University of Queensland in Brisbane and his colleagues attempted to do so by looking at twin pairs in which at least one sibling had been diagnosed with melanoma.

They searched through thousands of cases of melanoma reported in Queensland and New South Wales and found 125 twin pairs. In four of the 27 identical twin pairs, both had melanoma, while three of the 98 fraternal twin pairs had both been diagnosed with the deadly skin cancer.

Based on these numbers, having an identical twin with melanoma increased a person’s own risk of the disease nearly 10-fold, while melanoma associated with having a non-identical twin with the disease was roughly doubled.

This suggests, the researchers say, that some of the increased melanoma risk can be attributed to genes, in particular interactions between genes. They estimate that genes account for about half of the differences in risk between two people.

In the second study, Dr. Shehnaz K. Hussain of the University of California Los Angeles and colleagues looked at the Swedish Family-Cancer Database to gauge the risk for several types of skin cancer among siblings and children of people diagnosed with these diseases.

They found that people with a sibling or parent diagnosed with some types of skin cancer were more likely to develop skin cancers of various types, not just the ones their relatives had. When tumors occurred at parts of the body more likely to have been exposed to the sun (such as the face, compared to the torso), the familial risk was stronger.

Based on the findings, Hussain and colleagues conclude, a person’s family history can be used to gauge their own skin cancer risk, and genetic studies could be a useful way to identify potential targets for treating or preventing the disease.

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